The attached comment discusses Semantic eScience in the context of the Philosophy of Science and Joint Doctrine. In summary, The Philosophy of Science suggests that there are significant limitations to the predictive power of Semantic eScience; Semantic eScience could be more strongly aligned with Joint Doctrine. The effectiveness of Semantic eScience relative to other methods is not discussed because the effectiveness of Semantic eScience as a cybersecurity tool can only be established by field studies.