Abstract: This new CPS Synergy project is concerned with Management-Coupled Cyber and Physical Infrastructures (MCCPIs), which are infrastructures whose cyber- and physical- components are coupled by their wide-area management functions.  The main objective of the project is to develop a framework and tool set for threat assessment for MCCPIs which acknowledges their cyber, physical, and human elements, and to apply these tools and methods in a case study of the air traffic management system.  Three broad types of threats are considered: en