Infrastructure networks are the foundation of the modern world. Their continued reliable and efficient function without exhausting finite natural resources is critical to the security, continued growth and technological advancement of the United States. Currently these systems are in a state of rapid flux due to a collision of trends such as growing populations, expanding integration of information technology, and increasing motivation to adopt sustainable practices. These trends beget both exciting potential benefits and dangerous challenges.

Infrastructure networks are the foundation of the modern world. Their continued reliable and efficient function without exhausting finite natural resources is critical to the security, continued growth and technological advancement of the United States. Currently these systems are in a state of rapid flux due to a collision of trends such as growing populations, expanding integration of information technology, and increasing motivation to adopt sustainable practices. These trends beget both exciting potential benefits and dangerous challenges.

Epilepsy is one of the most common neurological disorders, affecting between 0.4% and 1% of the world's population. While seizures can be controlled in approximately two thirds of newly diagnosed patients through the use of one or more antiepileptic drugs (AEDs), the remainder experience seizures even on multiple medications. The primary impacts of the chronic condition of epilepsy on a patient are a lower quality of life, loss of productivity, comorbidities, and increased risk of death.

The timely and accurate in-service identification of faults in mechanical structures, such as airplanes, can play a vitally important role in avoiding catastrophes. One major challenge, however, is that the sensing system relies on high frequency signals, the coordination of which is difficult to achieve throughout a large structure. To tackle this fundamental issue, the research team will take advantage of 3D printing technology to fabricate integrated sensor-structure components.

Parking can take up a significant amount of the trip costs (time and money) in urban travel. As such, it can considerably influence travelers' choices of modes, locations, and time of travel. The advent of smart sensors, wireless communications, social media and big data analytics offers a unique opportunity to tap parking's influence on travel to make the transportation system more efficient, cleaner, and more resilient. A cyber-physical social system for parking is proposed to realize parking's potential in achieving the above goals.

Children affected by neurological conditions (e.g., Cerebral Palsy, Muscular Atrophy, Spina Bifida and Severe head trauma) often develop significant disabilities including impaired motor control. In many cases, walking becomes a non-functional and exhausting skill that demands the use of the aids or the substitution of function, such as wheelchair. This usually cause these children not to acquire locomotion skills, and consequently to lose their independence.

The project aims at making cities "smarter" by engineering processes such as traffic control, efficient parking services, and new urban activities such as recharging electric vehicles. To that end, the research will study the components needed to establish a Cyber-Physical Infrastructure for urban environments and address fundamental problems that involve data collection, resource allocation, real-time decision making, safety, and security.

Manufacturing and production have been big contributors to improved quality and sustainability of human life. Current market trends, such as consumer demand for variety, short product life cycles, high product quality and low cost, have resulted in the need for efficient, responsive, robust and sustainable manufacturing and production paradigm. 3D printing technologies hold the merit of affordability and customizability, while the key challenge in applying 3D printing for mass customization in real life is how to reduce the lead time per unit.

The evolution of manufacturing systems from loose collections of cyber and physical components into true cyber-physical systems has expanded the opportunities for cyber-attacks against manufacturing. To ensure the continued production of high-quality parts in this new environment requires the development of novel security tools that transcend both the cyber and physical worlds. Potential cyber-attacks can cause undetectable changes in a manufacturing system that can adversely affect the product's design intent, performance, quality, or perceived quality.

Strategic decision-making for physical-world infrastructures is rapidly transitioning toward a pervasively cyber-enabled paradigm, in which human stakeholders and automation leverage the cyber-infrastructure at large (including on-line data sources, cloud computing, and handheld devices). This changing paradigm is leading to tight coupling of the cyber- infrastructure with multiple physical- world infrastructures, including air transportation and electric power systems.