This project explores balancing performance considerations and power consumption in cyber-physical systems, through algorithms that switch among different modes of operation (e.g., low-power/high-power, on/off, or mobile/static) in response to environmental conditions. The main theoretical contribution is a computational, hybrid optimal control framework that is connected to a number of relevant target applications where physical modeling, control design, and software architectures all constitute important components. The fundamental research in this program advances state-of-the-art along four different dimensions, namely (1) real-time, hybrid optimal control algorithms for power management, (2) power-management in mobile sensor networks, (3) distributed power-aware architectures for infrastructure management, and (4) power-management in embedded multi-core processors. The expected outcome, which is to enable low-power devices to be deployed in a more effective manner, has implications on a number of application domains, including distributed sensor and communication networks, and intelligent and efficient buildings. The team represents both a research university (Georgia Institute of Technology) and an undergraduate teaching university (York College of Pennsylvania) in order to ensure that the educational components are far-reaching and cut across traditional educational boundaries. The project involves novel, inductive-based learning modules, where graduate students team with undergraduate researchers.

The focus of this project is the efficient implementation of multiple control and non-control automotive applications in a distributed embedded system (DES) with a goal of developing safe, dependable, and secure Automotive CPS. DES are highly attractive due to the fact that they radically enhance the capabilities of the underlying system by linking a range of devices and sensors and allowing information to be processed in unprecedented ways. Deploying control and non-control applications on a modern DES, which uses advanced processor and communication technology, introduces a host of challenges in their analysis and synthesis, and leads to a large semantic gap between models and their implementation. This gap will be filled via the development of a novel CPS architecture by stitching together common fundamental principles of multimodality from real-time systems and related notions of switching in control theory and integrating them into a co-design of real-time platforms and adaptive controllers. This architecture will be validated at the Toyota Technical Center in the context of engine control and diagnostics. The results of this project will provide the science and technology for a foundation in any and all infrastructure systems ranging from finance and energy to telecommunication and transportation where distributed embedded systems are present. In addition to training the graduate and undergraduate students, and mentoring a post-doctoral associate who will gain multi-domain expertise in advanced control, real-time computation and communication, and performance analysis, an inter-school graduate and an integrated summer course will be developed on control in embedded systems and combined with on-going outreach programs at MIT and UPenn for minority and women undergraduate students and K-12 students.

Holonic Multi-Agent Control of Intelligent Power Distribution Systems This project will demonstrate a Holonic Multiagent System Architecture capable of adaptively controlling future electrical power distribution systems (PDS), which are expected to include a large number of renewable power generators, energy storage devices, and advanced metering and control devices. The project will produce a general, extensible, and secure cyber architecture based on holonic multiagent principles to support adaptive PDS. It will produce new analytical insights to quantify the impact of information delay, quality and flow on the design and analysis of the PDS architecture. Finally, it will develop a novel approach to automating PDS with high penetration of distributed renewable resources for higher efficiency, reliability, security, and resiliency. The complex nature of future PDS will require them to adapt reactively and proactively to normal and anomalous modes of operation. The architecture produced by this project will be capable of optimizing performance and maintaining the system within operating limits during normal and minor events, such as cloud cover that reduces solar panels output. The architecture will also allow the operation of a distribution system as an island in emergencies, such as hurricanes/earthquakes, grid failures, or terrorist acts. The project will inspire future engineers via a simulation that will allow students to inject faults, failures, and weather events to see how an intelligent PDS will respond. These activities will combine cyber- and physical expertise, thus creating a workforce prepared for tomorrow?s cyber-physical system challenges. Existing university programs will be used to involve under-represented minorities and U.S. veterans in the project.

This project integrates digital microfluidics with thin-film photodetectors and control software to realize DNA target sensing using fluorescence. This cyberphysical vision is being realized through tight coupling between physical components, the microfluidic platform and miniaturized sensors, and cyber components, software for control, decision-making, and adaptation. Such a level of integration, decision, and controlled reconfigurability is a significant step forward in clinical diagnostics using digital microfluidic biochips. Topics being investigated include: (i) silicon-based digital microfluidics and integration of optical sensors; (ii) closed-loop operation and run-time optimization under software control; (iii) decision-tree architectures, adaptive reconfiguration, and error recovery. A complete testbed is being developed for nucleic acid identification on a fabricated chip with detection sites. Cyberphysical system integration will transform biochip use, in the same way as compilers and operating systems revolutionized computing, and design automation revolutionized chip design. Benefits to society include the potential to transform personalized medicine, home diagnostics, and portable diagnostics. Integration of digital microfluidics, optical sensing, and software control has the potential to create systems that can be used by any person, regardless of sample preparation skill. One example is the identification of bacterial DNA associated with bacterial blood infection (sepsis), which results in death if not diagnosed early (this is in the top 10 causes of death in the US). Students are being trained through a Senior Design course to understand the design