The objective of this research is to design a semi-automated, efficient, and secure emergency response system to reduce the time it takes emergency vehicles to reach their destinations, while increasing the safety of non-emergency vehicles and emergency vehicles alike. Providing route and maneuver guidance to emergency vehicles and non-emergency vehicles will make emergency travel safer and enable police and other first responders to reach and transport those in need, in less time. This should reduce the number of crashes involving emergency vehicles and associated litigation costs while improving medical outcomes, reducing property damage, and instilling greater public confidence in emergency services. At the same time, non-emergency vehicles will also be offered increased safety and, with the reduction of long delays attributed to emergency vehicles, experience reduced incident-related travel time, which will increase productivity and quality of life for drivers. Incorporating connected vehicles into the emergency response system will also provide synergistic opportunities for non-emergency vehicles, including live updates on accident sites, areas to avoid, and information on emergency routes that can be incorporated into navigation software so drivers can avoid potential delays. While the proposed system will naturally advance the quality of transportation in smart cities, it will also provide a platform for future techniques to build upon. For example, the proposed system could be connected with emergency care facilities to balance the load of emergency patients at hospitals, and act as a catalyst toward the realization of a fully-automated emergency response system. New courses and course modules will be developed to recruit and better prepare a future workforce that is well versed in multi-disciplinary collaborations. Video demos and a testbed will be used to showcase the research to the public. The key research component will be the design of an emergency response system that (1) dynamically determines EV routes, (2) coordinates actions by non-emergency vehicles using connected vehicle technology to efficiently and effectively clear paths for emergency vehicles, (3) is able to adapt to uncertain traffic and network conditions, and (4) is difficult to abuse or compromise. The project will result in (1) algorithms that dynamically select EV routes based on uncertain or limited traffic data, (2) emergency protocols that exploit connected vehicle technology to facilitate emergency vehicles maneuvers, (3) an automation module to assist with decision making and maneuvers, and (4) an infrastructure and vehicle hardening framework that prevents cyber abuse. Experiments will be performed on a testbed and a real test track to validate the proposed research.

The goal of this project is to facilitate timely retrieval of dynamic situational awareness information from field-deployed nodes by an operational center in resource-constrained uncertain environments, such as those encountered in disaster recovery or search and rescue missions. This is an important cyber physical system problem with perspectives drawn at a system and platform level, as well as at the system of systems level. Technology advances allow the deployment of field nodes capable of returning rich content (e.g., video/images) that can significantly aid rescue and recovery. However, development of techniques for acquisition, processing and extraction of the content that is relevant to the operation under resource constraints poses significant interdisciplinary challenges, which this project will address. The focus of the project will be on the fundamental science behind these tasks, facilitated by validation via both in house experimentation, and field tests orchestrated based on input from domain experts. In order to realize the vision of this project, a set of algorithms and protocols will be developed to: (a) intelligently activate field sensors and acquire and process the data to extract semantically relevant information; (b) formulate expressive and effective queries that enable the near-real-time retrieval of relevant situational awareness information while adhering to resource constraints; and, (c) impose a network structure that facilitates cost-effective query propagation and response retrieval. The research brings together multiple sub-disciplines in computing sciences including computer vision, data mining, databases and networking, and understanding the scientific principles behind information management with compromised computation/communication resources. The project will have a significant broader impact in the delivery of effective situational awareness in applications like disaster response. The recent :World Disaster Report" states that there were more than 1 million deaths and $1.5 trillion in damage from disasters within the past decade; the research has the potential to drastically reduce these numbers. Other possible applications are law enforcement and environmental monitoring. The project will facilitate a strong inter-disciplinary education program and provide both undergraduate and graduate students experience with experimentation and prototype development. There will be a strong emphasis on engaging the broader community and partnering with programs that target under-represented students and minorities.

During the last decade, we have witnessed a rapid penetration of autonomous systems technology into aerial, road, underwater, and sea vehicles. The autonomy assumed by these vehicles holds the potential to increase performance significantly, for instance, by reducing delays and increasing capacity, while enhancing safety, in a number of transportation systems. However, to exploit the full potential of these autonomy-enabled transportation systems, we must rethink transportation networks and control algorithms that coordinate autonomous vehicles operating on such networks. This project focuses on the design and operation of autonomy-enabled transportation networks that provide provable guarantees on achieving high performance and maintaining safety at all times. The foundational problems arising in this domain involve taking into account the physics governing the vehicles in order to coordinate them using cyber means. This research effort aims to advance the science of cyber-physical systems by following a unique and radical approach, drawing inspiration and techniques from non-equilibrium statistical mechanics and self-organizing systems, and blending this inspiration with the foundational tools of queueing theory, control theory, and optimization. This approach may allow orders of magnitude improvement in the servicing capabilities of various transportation networks for moving goods or people. The applications include the automation of warehouses, factory floors, sea ports, aircraft carrier decks, transportation networks involving driverless cars, drone-enabled delivery networks, air traffic management, and military logistics networks. The project also aims to start a new wave of classes and tutorials that will create trained engineers and a research community in the area of safe and efficient transportation networks enabled by autonomous cyber-physical systems.

Many practical systems such as smart grid, unmanned aerial vehicles (UAVs) and robotic networks can be categorized as cyber physical systems (CPS). A typical CPS consists of physical dynamics, sensors, communication network and controllers. The communication network is of key importance in CPS, since it mimics the nerve system in the human body. Hence, it is critical to study how the communication network in CPS should be analyzed and designed. Essentially, communications stem from the uncertainty of system under consideration; random perturbations increase the system uncertainty, which is reduced by the control actions in CPS. It is well known that entropy is a measure of system uncertainty. A unified framework of entropy is used for CPS, in which random perturbations create entropy while communications and controls provide negative entropy to compensate the entropy generation. The intellectual merits are the novel framework of entropy for bridging the communications and control in CPS and the new design criterion based on the entropy of system state for CPS. The project's broader significance and importance are the education of various levels of students, the dissemination of results to public, and the impact on everyday life such as the improved agility and robustness of power grids. This project applies the framework of entropy to study the interdependencies of communications and control, thus facilitating the analysis and design of communications in CPS. The following tasks are tackled in the project: (a) Entropy Flow Based Communication Capacity Analysis in which communications in CPS is analyzed by studying the entropy fields in the physical dynamics, thus providing an estimation on the scale (bits/second) of communication capacity budget; (b) Communication Network Topology Design in which the design of the network topology (either physical or logical) is tackled through both optimization-based or heuristic approaches; (c) Online Network Resource Scheduling which refines the network resource scheduling during the operation using both optimization-based and heuristic approaches, within the framework of entropy fields; (d) Hardware Emulation Testbed which delivers a co-simulation testbed based on real time digital power simulator (RTDS) and a communication simulator, in the context of smart grids. Based on the research, new courses are developed. K-12 outreach and various levels of undergraduate/graduate educations are incorporated into the research.

Security and privacy concerns in the increasingly interconnected world are receiving much attention from the research community, policymakers, and general public. However, much of the recent and on-going efforts concentrate on security of general-purpose computation and on privacy in communication and social interactions. The advent of cyber-physical systems (e.g., safety-critical IoT), which aim at tight integration between distributed computational intelligence, communication networks, physical world, and human actors, opens new horizons for intelligent systems with advanced capabilities. These systems may reduce number of accidents and increase throughput of transportation networks, improve patient safety, mitigate caregiver errors, enable personalized treatments, and allow older adults to age in their places. At the same time, cyber-physical systems introduce new challenges and concerns about safety, security, and privacy. The proposed project will lead to safer, more secure and privacy preserving CPS. As our lives depend more and more on these systems, specifically in automotive, medical, and Internet-of-Things domains, results obtained in this project will have a direct impact on the society at large. The study of emerging legal and ethical aspects of large-scale CPS deployments will inform future policy decision-making. The educational and outreach aspects of this project will help us build a workforce that is better prepared to address the security and privacy needs of the ever-more connected and technologically oriented society. Cyber-physical systems (CPS) involve tight integration of computational nodes, connected by one or more communication networks, the physical environment of these nodes, and human users of the system, who interact with both the computational part of the system and the physical environment. Attacks on a CPS system may affect all of its components: computational nodes and communication networks are subject to malicious intrusions, and physical environment may be maliciously altered. CPS-specific security challenges arise from two perspectives. On the one hand, conventional information security approaches can be used to prevent intrusions, but attackers can still affect the system via the physical environment. Resource constraints, inherent in many CPS domains, may prevent heavy-duty security approaches from being deployed. This proposal will develop a framework in which the mix of prevention, detection and recovery, and robust techniques work together to improve the security and privacy of CPS. Specific research products will include techniques providing: 1) accountability-based detection and bounded-time recovery from malicious attacks to CPS, complemented by novel preventive techniques based on lightweight cryptography; 2) security-aware control design based on attack resilient state estimator and sensor fusions; 3) privacy of data collected and used by CPS based on differential privacy; and, 4) evidence-based framework for CPS security and privacy assurance, taking into account the operating context of the system and human factors. Case studies will be performed in applications with autonomous features of vehicles, internal and external vehicle networks, medical device interoperability, and smart connected medical home.

This research addresses the science of Cyber-Physical Systems. In a multi-agent system, each agent is faced with the task of making decisions taking account of the objectives and actions of other agents, as well as the dynamics of the environment. In such a distributed system each agent receives measurements of its environment, and must infer both the state of the world as well as that of the other agents. The intellectual merits of this research are that it develops new efficient techniques for this information processing, which achieve run-time performance using algorithms that have low computational requirements. The project's broader significance and importance are that it will provide new mathematical and computational tools for use in many engineering applications, including the power grid, transportation networks, and other multi-agent systems, and will be transitioned to practice through professional activities such as workshops, development of educational material for graduates, undergraduates and teenagers, and outreach to industry. The underlying mathematical and computation tools for this research are based on new methods for statistical filtering in a dynamic setting. One of the most important techniques for the design of software control systems constructs state estimates which are sufficient statistics for the associated decision problem. However, conventional approaches to sufficient statistics and state estimation do not apply to the multi-agent setting. Recent results have given new sufficient statistics for this setting, and the research develops the theory and algorithms to allow these statistics to be used for multi-agent control of cyber-physical systems.

During the last decade, we have witnessed a rapid penetration of autonomous systems technology into aerial, road, underwater, and sea vehicles. The autonomy assumed by these vehicles holds the potential to increase performance significantly, for instance, by reducing delays and increasing capacity, while enhancing safety, in a number of transportation systems. However, to exploit the full potential of these autonomy-enabled transportation systems, we must rethink transportation networks and control algorithms that coordinate autonomous vehicles operating on such networks. This project focuses on the design and operation of autonomy-enabled transportation networks that provide provable guarantees on achieving high performance and maintaining safety at all times. The foundational problems arising in this domain involve taking into account the physics governing the vehicles in order to coordinate them using cyber means. This research effort aims to advance the science of cyber-physical systems by following a unique and radical approach, drawing inspiration and techniques from non-equilibrium statistical mechanics and self-organizing systems, and blending this inspiration with the foundational tools of queueing theory, control theory, and optimization. This approach may allow orders of magnitude improvement in the servicing capabilities of various transportation networks for moving goods or people. The applications include the automation of warehouses, factory floors, sea ports, aircraft carrier decks, transportation networks involving driverless cars, drone-enabled delivery networks, air traffic management, and military logistics networks. The project also aims to start a new wave of classes and tutorials that will create trained engineers and a research community in the area of safe and efficient transportation networks enabled by autonomous cyber-physical systems.

Smart grid includes two interdependent infrastructures: power transmission and distribution network, and the supporting telecommunications network. Complex interactions among these infrastructures lead to new pathways for attack and failure propagation that are currently not well understood. This innovative project takes a holistic multilevel approach to understand and characterize the interdependencies between these two infrastructures, and devise mechanisms to enhance their robustness. Specifically, the project has four goals. The first goal is to understand the standardized smart grid communications protocols in depth and examine mechanisms to harden them. This is essential since the current protocols are notoriously easy to attack. The second goal is to ensure robustness in state estimation techniques since they form the basis for much of the analysis of smart grid. In particular, the project shall exploit a steganography-based approach to detect bad data and compromised devices. The third goal is to explore trust-based attack detection strategies that combine the secure state estimation with power flow models and software attestation to detect and isolate compromised components. The final goal is to study reconfiguration strategies that combine light-weight prediction models, stochastic decision processes, intentional islanding, and game theory techniques to mitigate the spreading of failures and the loss of load. A unique aspect of smart grid security that will be studied in this project is the critical importance of timeliness, and thus a tradeoff between effectiveness of the mechanisms and the overhead introduced. The project is expected to provide practical techniques for making the smart grid more robust against failures and attacks, and enable it to recover from large scale failures with less loss of capacity. The project will also train students in the multidisciplinary areas of power systems operation and design, networking protocols, and cyber-physical security.

Epilepsy is one of the most common neurological disorders, affecting between 0.4% and 1% of the world's population. While seizures can be controlled in approximately two thirds of newly diagnosed patients through the use of one or more antiepileptic drugs (AEDs), the remainder experience seizures even on multiple medications. The primary impacts of the chronic condition of epilepsy on a patient are a lower quality of life, loss of productivity, comorbidities, and increased risk of death. Epilepsy is an intermittent brain disorder, and in localization-related epilepsy, which is the most common form of epilepsy, one or a few discrete brain areas (the seizure focus or seizure foci) are believed to be responsible for seizure initiation. More recent approaches with implantable electrical stimulation seizure control devices hold value as a therapeutic option for the control of seizures. These devices, directly or indirectly, target the seizure focus and seek to control its expression. In this project we will build a multichannel brain implantable device based on emerging cyber physical system (CPS) principles. This brain implantable CPS device will incorporate key design features to make the device dependable, scalable, composable, certifiable, and interoperable. The device will operate over the life of an animal, or a patient, and continuously record brain activity and stimulate the brain when seizure related activity is detected to abort an impending seizure. Episodic brain disorders such as epilepsy have a considerable impact on a patient's productivity and quality of life and may be life-threatening when seizures cannot be controlled with medications. The goal of this project is to create a second generation brain-implantable sensing and stimulating device (BISSD) based on emerging CPS principles and practice. The development of a BISSD as a exemplifies several defining aspects that inform and illustrate core CPS principles. First, to meet the important challenge of regulatory approval a composable, scalable and certifiable framework that supports testing in multiple species is proposed. Second, a BISSD must be wholly integrated with the patient and fully cognizant at every instant of brain state, including dynamic changes in both the normal and abnormal expression of brain physiology and therapeutic intervention. Thus, this project seeks a tight conjunction of the cyber solution that must monitor itself and monitor and stimulate the brain using implanted, adaptable, distributed, and networked electrodes, and the physical system which in this case is the intermittently failing human brain. Third, a BISSD must function for an extensive period of time, up to the life of the patient, because each surgery to place and retrieve a BISSD carries an attendant risk. This requirement necessitates a dependable solution, which this project seeks to reliably achieve through both an understanding of the brain's foreign body response and a unique hierarchical fault-tolerant design. Fourth, an advanced salient approaches to acquire, compress, and analyze sensor signals to achieve real-time monitoring and control of seizures is employed. This project should yield a powerful, scalable CPS framework for robust fault-tolerant implantable medical devices with real-time processing that can grow with advances in sensors, sensing modalities, time-series analysis, real-time computation, control, materials, power and knowledge of underlying biology. The USA has a competitive advantage in the control of seizures in medically refractory epilepsy. In the modern era, epilepsy surgery evolved in the USA in the 1970s and spread from here to other parts of the world. Similarly, the USA enjoys a competitive advantage in BISSDs, and success in this effort will enable the USA to build on and maintain this advantage. In addition to epilepsy, advances made here can be expected to benefit the treatment of other neurological and psychiatric brain disorders.